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Minerva Y. Wong, Ph.D. PDF Print

Minerva Wong received her B.S. degree in Biomedical Engineering from Columbia University in 2005, and her M.A. degree in 2007, M.Phil. degree in 2009, and Ph.D. degree in 2013, all in Pharmacology and Molecular Signaling from Columbia University. Dr. Wong’s research encompassed the areas of cardiovascular and neurological diseases. Dr. Wong’s graduate studies and post-doctoral work focused on synaptic function, development of new technologies for studying biological diseases, and novel therapeutics for Parkinson’s disease. Dr. Wong was a recipient of a Columbia University Clinical and Translational Science Award.

Publications:

Rodriguez P.C., Pereira D.B., Borgkvist A., Wong M.Y.Barnard C., Sonders M.S., Zhang H., Sames D., Sulzer D. Fluorescent Dopamine Tracer Resolves Individual Dopaminergic Synapses and their Activity in the Brain. PNAS 2013; 110(3): 870-875.

Wong M.Y., Sulzer D., Bamford N.S. Imaging Presynaptic Exocytosis in Corticostriatal Slices. Methods Mol. Biol. 2011; 793: 363-376.

Zhang H., Gubernator N.G., Yue M., Staal R.G., Mosharov E.V., Pereira D., Balsanek V., Vadola P.A., Mukherjee B., Edwards R.H., Sulzer D., Sames D. Dopamine Release at Individual Presynaptic Terminals Visualized with FFNs. J. Vis. Exp. 2009; 30: 1562.

Gubernator N.G., Zhang H., Staal R.G., Mosharov E.V., Pereira D.B., Yue M., Balsanek V., Vadola P.A., Mukherjee B., Edwards R.H., Sulzer D., Sames D. Fluorescent False Neurotransmitters Visualize Dopamine Release from Individual Presynaptic Terminals. Science 2009; 324(5933):1441-1444.

Trudell J.R., Yue M., Bertaccini E.J., Jenkins A., Harrison N.L. Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn2+ in GABA(A) Alpha-Beta Receptors and Provides a Structural Basis for the Modulating Effect of the Gamma Subunit. J. Chem. Inf. Model. 2008; 48(2):344-349.

Jia F., Yue M., Chandra D., Keramidas A., Goldstein P.A., Homanics G.E., Harrison N.L. Taurine is a Potent Modulator of Extrasynaptic GABA(A) receptors in the Thalamus. J. Neurosci. 2008; 28(1):106-115.

Jia F., Yue M., Chandra D., Homanics G.E., Goldstein P.A., Harrison N.L. Isoflurane is a Potent Modulator of Extrasynaptic GABA(A) Receptors in the Thalamus. J. Pharmacol. Exp. Ther. 2008; 324(3):1127-1135.

Yue M., Bankston J.R., Chung W., Spyres M., Pass R.H., Silver E., Sampson K.J., Kass R.S. A Novel and Lethal de novo LQT-3 Mutation in a Newborn with Distinct Molecular Pharmacology and Therapeutic Response. PLoS One 2007; 2(12):e1258.

Jia F., Pignataro L., Schofield C.M., Yue M., Harrison N.L., Goldstein P.A. An Extrasynaptic GABA(A) Receptor Mediates Tonic Inhibition in Thalamic VB Neurons. J. Neurophysiol. 2005; 94(6):4491-4501.